TDZD 8

  
Catalog Number:6092
Alternate Names:NP 01139
Chemical Name:2-Methyl-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione
Product Details
Reviews
Biological Activity
Selective non-ATP competitive inhibitor of GSK 3β (IC50 = 2 μM); thiadiazolidinone deriviative. Does not inhibit Cdk-1/cyclin B, CK-II, PKA or PKC at >100 μM. Reduces severity of L-dopa-induced dyskinesia in a Parkinson's disease in vivo model.
Technical Data
  • M.Wt:
    222.26
  • Formula:
    C10H10N2O2S
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    327036-89-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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