Telenzepine dihydrochloride

Key Product Details

Product Description

Telenzepine dihydrochloride is a selective high affinity muscarinic M₁ receptor antagonist (K_i = 0.94 nM). Inhibits gastric acid secretion.

Product Specifications for Telenzepine dihydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Telenzepine dihydrochloride

The following data is based on the product molecular weight 443.39.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

6 5 4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.26 mL	11.28 mL	22.55 mL
5 mM	0.45 mL	2.26 mL	4.51 mL
10 mM	0.23 mL	1.13 mL	2.26 mL
50 mM	0.05 mL	0.23 mL	0.45 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 14 publications citing the usage of this product.

• Eltze Pharmacological evidence for selective inhibition of gastric acid secretion by telenzepine, a new antimuscarinic drug. Eur.J.Pharmacol. 1985 PMID: 4029260
• Galvan Interaction of telenzepine with muscarinic receptors in mammalian sympathetic ganglia. Eur.J.Pharmacol. 1989 PMID: 2776837
• Christofi Neuropharmacology of the muscarinic antagonist telenzepine in myenteric ganglia of the guinea-pig small intestine. Eur.J.Pharmacol. 1991 PMID: 1868879

Product Documents for Telenzepine dihydrochloride