Catalog Number: 1122
Chemical Name: 4,9-Dihydro-3-methyl-4-[(4-methyl-1-piperazinyl)acetyl]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one dihydrochloride
Biological Activity
Selective high affinity muscarinic M1 receptor antagonist (Ki = 0.94 nM). Inhibits gastric acid secretion.
Technical Data
  • M.Wt:
    443.39
  • Formula:
    C19H22N4O2S.2HCl
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Store at RT
  • CAS No:
    147416-96-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Interaction of telenzepine with muscarinic receptors in mammalian sympathetic ganglia.
    Galvan et al.
    Eur.J.Pharmacol., 1989;167:1
  2. Pharmacological evidence for selective inhibition of gastric acid secretion by telenzepine, a new antimuscarinic drug.
    Eltze et al.
    Eur.J.Pharmacol., 1985;112:211
  3. Neuropharmacology of the muscarinic antagonist telenzepine in myenteric ganglia of the guinea-pig small intestine.
    Christofi et al.
    Eur.J.Pharmacol., 1991;195:333
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Telenzepine dihydrochloride include:

1 Citations: Showing 1 - 1

  1. Dynamic regulation of quaternary organization of the M1 muscarinic receptor by subtype-selective antagonist drugs.
    Authors: Pediani Et al.
    J.Biol.Chem. 2016;291:13132

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