Chemical Name: 4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid
Biological ActivityAntagonist of the angiotensin II type 1 receptor (AT1) (Ki = 3.7 nM). Exhibits antihypertensive activity in a renin-dependent model of hypertension. Partial agonist of PPARγ receptors; shown to improve insulin sensitivity in rodents receiving high fat diets.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
An adipose tissue-independent Ins-sensitizing action of telmisartan: a study in lipodystrophic mice.
Rong et al.
6-substituted benzimidazoles as new nonpeptide angiotensin II receptor antagonists: synthesis, biological activity, and structure-activity relationships.
Ries et al.
Identification of telmis. as a unique angiotensin II receptor antagonist with selective PPAR γ-modulating activity.
Benson et al.
Citation for Telmisartan
The citations listed below are publications that use Tocris products. Selected citations for Telmisartan include:
1 Citation: Showing 1 - 1
Development of telmis. in the therapy of spinal cord injury: pre-clinical study in rats.
Authors: Lin Et al.
Psychopharmacology (Berl) 2015;9:4709
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