TGX 221

Catalog # Availability Size / Price Qty
5832/10
5832/50
Cat.No. 5832 - TGX 221 | C21H24N4O2 | CAS No. 663619-89-4
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Description: Potent and selective PI 3-kinase β inhibitor

Chemical Name: 7-Methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one

Purity: ≥98%

Product Details
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Biological Activity

Potent and selective PI 3-kinase β inhibitor (IC50 values are 0.007, 0.1, 3.5 and 5 μM for the β, δ, γ and α isoforms, respectively). Shows >1,000-fold selectively for PI 3-kinase β over a range of other kinases. Inhibits thrombus formation in animal models.

Technical Data

M.Wt:
364.44
Formula:
C21H24N4O2
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
663619-89-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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