TH 1217
Chemical Name: 2-[4-[[5,6-Dichloro-2-methyl-4-nitro-1H-benzo[d]-imidazol-1-yl]methyl]phenyl]-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione
Purity: ≥98%
Biological Activity
TH 1217 is a potent dCTPase pyrophosphatase 1 inhibitor (IC50 = 47 nM).TH 1217 is not stable in aqueous solution. It is recommended that fresh samples are prepared and used immediately.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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Additional Information
Background References
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Discovery of the first potent and selective inhibitors of human dCTP pyrophosphatase 1.
Llona-Minguez et al.
J.Med.Chem., 2016;59:1140
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