Chemical Name: 5-(Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine hydrochloride
Biological ActivityTizanidine hydrochloride is an α2-adrenergic receptor agonist. Antinociceptive upon epidural administration in rats (IC50 = 48 nM). Also binds to imidazoline receptor.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Antinociception by epidural and systemic α2-adrenoceptor agonists and their binding affinity in rat spinal cord and brain.
Asano et al.
Autoradiographic comparison of [3H]-Clonidine binding to non-adrenergic sites and α2-adrenergic receptors in human brain.
Piletz et al.
Citation for Tizanidine hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Tizanidine hydrochloride include:
1 Citation: Showing 1 - 1
Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses.
Authors: Thomas C Et al.
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