Recombinant Human TNNC2 Protein

Name: Recombinant Human TNNC2 Protein
Brand: Novus Biologicals
SKU: NBC1-28768
Price: 349 USD
Availability: InStock

Novus Biologicals | Catalog # NBC1-28768

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Applications

SDS-PAGE

View all Troponin C Proteins and Enzymes »

Product Specifications

Description

An un-tagged recombinant protein corresponding to the amino acids1-160 of E.coli Troponin C (skeletal muscle)

Source: E.coli

Amino Acid Sequence: MTDQQAEARS YLSEEMIAEF KAAFDMFDAD GGGDISVKEL GTVMRMLGQT PTKEELDAII EEVDEDGSGT IDFEEFLVMM VRQMKEDAKG KSEEELAECF RIFDRNADGY IDPEELAEIF RASGEHVTDE EIESLMKDGD KNNDGRIDFD EFLKMMEGVQ

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

18.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human TNNC2 Protein

SDS-Page: Recombinant Human TNNC2 Protein [NBC1-28768] -

SDS-Page: Recombinant Human TNNC2 Protein [NBC1-28768] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation, and Storage

NBC1-28768

Formulation	20 mM Tris-HCl buffer (pH 7.5), 1 mM DTT, 100 mM NaCl, 10% glycerol
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Troponin C

Troponin C, skeletal muscle, also known as TNNC2, is the central regulatory protein of striated muscle contraction, and modulates the Ca2+-activation characteristics of muscle fibers. Troponin has 3 subunits, Troponin I(Tn-1), Troponin T(Tn-T) and Troponin C(Tn-C). Tn-I subunit inhibits actomyosin ATPase and Tn-T subunit binds tropomyosin and Tn-C, while Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. Mutations in all components of this complex have been associated with skeletal muscle disease. Recombinant human Troponin C was expressed in E.coli and purified by using conventional chromatography.

Alternate Names

Tn-C, TNNC2

Gene Symbol

TNNC2

Additional Troponin C Products

Product Documents for Recombinant Human TNNC2 Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Human TNNC2 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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