Tocriscreen Kinase Inhibitor Library

Catalog # Availability Size / Price Qty
6268/1 SET
Tocriscreen Kinase Inhibitor Library | Compound Libraries
1 Image
Description: A bioactive compound library of 160 kinase inhibitors (250 μL 10 mM DMSO solutions) for high-throughput screening, high-content screening and chemical biology applications
Product Details
Citations (12)
Reviews

Biological Activity

Tocriscreen Kinase Inhibitor Library is a collection of 160 kinase inhibitors supplied pre-dissolved in DMSO (250 μL 10 mM solution). The Tocriscreen Kinase Inhibitor Library contains compounds targeting >60 different kinases, including extensive coverage of well-established targets such as VEFGR, AKT and TGFβR as well as more novel targets such as LIMK, Hapsin, NUAK1 and DYRK.

If this library does not suit your needs, please submit your requirements through our Tocriscreen PRO custom compound library service.

Key Format and Product Details

  • 96-well racks with Matrix storage tubes & SepraSeal caps
  • Pre-dissolved in DMSO
  • Compounds arranged 80 per rack with two racks per library
  • Many compounds are exclusive to Tocris
  • Full chemical and biological data available
  • Exceptional purity
Target Classes Covered by the Tocriscreen Kinases Inhibitors Library

The Tocriscreen Kinase Inhibitors Library contains bioactive compounds covering a diverse range of kinases, including established enzymes and more novel targets.

Request Compound List

A list of the compounds available in the Tocriscreen Kinase Inhibitor Library can be requested in Excel or SD format via our Tocriscreen & Custom Library Inquiries form.

Technical Data

Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Other Product-Specific Information:
The Compound list for this product may be requested from www.tocris.com/screening

Product Datasheets

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Citations for Tocriscreen Kinase Inhibitor Library

The citations listed below are publications that use Tocris products. Selected citations for Tocriscreen Kinase Inhibitor Library include:

12 Citations: Showing 1 - 10

  1. Chemical manipulation of abscisic acid signaling: a new approach to abiotic and biotic stress management in agriculture.
    Authors: Hewage Et al.
    Adv.Sci.  2020;7:2001265
  2. A Novel Three-Dimensional Glioma Blood-Brain Barrier Model for High-Throughput Testing of Tumoricidal Capability.
    Authors: Sherman and Rossi
    Front Oncol  2019;9:351
  3. NTRK1 is a positive regulator of YAP oncogenic function.
    Authors: Yang Et al.
    Oncogene  2019;38:2778
  4. Transient c-Src Suppression During Endodermal Commitment of Human Induced Pluripotent Stem Cells Results in Abnormal Profibrotic Cholangiocyte-Like Cells.
    Authors: Chaudhari Et al.
    Stem Cells  2019;37:306
  5. A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis.
    Authors: Azad Et al.
    Nat Commun  2018;9:1061
  6. GSK3 is a negative regulator of the thermogenic program in brown adipocytes.
    Authors: Markussen Et al.
    Sci.Rep.  2018;8:3469
  7. 1-Benzyl-3-cetyl-2-methylimidazolium Iodide (NH125) Is a Broad-Spectrum Inhibitor of Virus Entry with Lysosomotropic Features.
    Authors: Moeschler Et al.
    Viruses  2018;10:E306
  8. p70S6K is regulated by focal adhesion kinase and is required for Src-selective autophagy.
    Authors: Sandilands Et al.
    Cell Signal.  2015;27:1816
  9. SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest.
    Authors: Tandon Et al.
    PLoS One  2015;10:e0119346
  10. A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response.
    Authors: FitzGerald Et al.
    PLoS One  2014;9:e98891

FAQs

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