TP 238

Tocris Bioscience | Catalog # 6670

CECR2 and BPTF/FALZ inhibitor
Tocris Bioscience
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Key Product Details

Description

CECR2 and BPTF/FALZ inhibitor

Product Description

TP 238 is a cat eye syndrome chromosome region, candidate 2 (CECR2) and bromodomain PHD finger transcription factor (BPTF/FALZ) inhibitor (IC50 values are 10-30 and 100-350 nM, respectively).

A concentration of no more than 2 μM is recommended for use in cellular assays.

Licensing Information

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the TP 238 probe summary on the SGC website.

Product Specifications for TP 238

Molecular Weight

495.04

Formula

C22H30N6Osub>3S.HCl

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

N-[(3-(1H)-Pyrazol-1-yl)propyl)-6-(4-(3-(dimethylamino)propoxy)phenyl)-2-(methylsulfonyl)pyrimidin-4-amine hydrochloride

CAS Number

2415263-05-5

SMILES

O=S(C1=NC(NCCCN2N=CC=C2)=CC(C3=CC=C(C=C3)OCCCN(C)C)=N1)(C)=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 49.5 100
DMSO 49.5 100

Preparing Stock Solutions for TP 238

The following data is based on the product molecular weight 495.04.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.02 mL 10.10 mL 20.20 mL
5 mM 0.40 mL 2.02 mL 4.04 mL
10 mM 0.20 mL 1.01 mL 2.02 mL
50 mM 0.04 mL 0.20 mL 0.40 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

There are currently no references for this product.

Product Documents for TP 238

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TP 238

For research use only

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