Catalog Number: 4218
Chemical Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid 1-methyethyl ester
Biological Activity
FP prostaglandin receptor agonist. Exhibits submicromolar affinity for DP, EP, IP and TP receptors. Stimulates intracellular Ca2+ mobilization. Ocular hypotensive agent.
Technical Data
  • M.Wt:
    500.55
  • Formula:
    C26H35F3O6
  • Solubility:
    Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 10mg/ml)
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    157283-68-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. [3H]AL-5848 ([3H]9beta-(+)-Fluprostenol). Carboxylic acid of travoprost (AL-6221), a novel FP prostaglandin to study the pharmacology and autoradiographic localization of the FP receptor.
    Sharif et al.
    J.Pharm.Pharmacol., 1999;51:685
  2. Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist.
    Hellberg et al.
    J.Ocul.Pharmacol.Ther., 2001;17:421

Have you used Travaprost?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 

Feedback

Customer Information