Chemical Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid 1-methyethyl ester
Biological ActivityFP prostaglandin receptor agonist. Exhibits submicromolar affinity for DP, EP, IP and TP receptors. Stimulates intracellular Ca2+ mobilization. Ocular hypotensive agent.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist.
Hellberg et al.
[3H]AL-5848 ([3H]9beta-(+)-Fluprostenol). Carboxylic acid of travo. (AL-6221), a novel FP prostaglandin to study the pharmacology and autoradiographic localization of the FP receptor.
Sharif et al.
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