Selective and potent inhibitor of histone deacetylase (Ki
= 3.4 nM). Active in vivo
. Potential anti-cancer agent. Induces accelerated dedifferentiation of primordial germ cells (PGCs) into embryonic germ (EG) cells.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Reprogramming primordial germ cells into pluripotent stem cells.
Durcova-Hills et al.
PloS ONE, 2008;3:e3531
Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A.
Yoshida et al.
Inhibition of mitogenesis in Balb/c-3T3 cells by trichostatin A.
Wharton et al.
Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo.
Vigushin et al.
Clin.Cancer Res., 2001;7:971
The citations listed below are publications that use Tocris products. Selected citations for Trichostatin A include:
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