TROP-2 Antibody (MM0588-49D6) [Alexa Fluor® 647]

Novus Biologicals | Catalog # NBP2-11982AF647

Novus Biologicals
Discontinued Product
NBP2-11982AF647 has been discontinued. View all TROP-2 products.

Key Product Details

Validated by

Biological Validation

Species Reactivity

Human

Applications

Western Blot, Flow Cytometry, CyTOF-ready

Label

Alexa Fluor 647 (Excitation = 650 nm, Emission = 668 nm)

Antibody Source

Monoclonal Mouse IgG2 Clone # MM0588-49D6
View all TROP-2 Primary Antibodies »

Product Specifications

Immunogen

Human recombinant TROP-2

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2

Scientific Data Images for TROP-2 Antibody (MM0588-49D6) [Alexa Fluor® 647]

TROP-2 Antibody (MM0588-49D6) [Alexa Fluor® 647]

Flow Cytometry: Mouse Monoclonal TROP-2 Antibody (MM0588-49D6) [Alexa Fluor® 647] [NBP2-11982AF647] -

Flow Cytometry: Mouse Monoclonal TROP-2 Antibody (MM0588-49D6) [Alexa Fluor® 647] [NBP2-11982AF647] - Detection of human TROP-2 on A431 epidermoid carcinoma cells. A431 cells were treated with the TROP-2 AF647 antibody (catalog # NBP2-11982AF647) (BLUE) or mouse IgG2 AF647 isotype control antibody (RED). Image from a verified customer review.

Applications for TROP-2 Antibody (MM0588-49D6) [Alexa Fluor® 647]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 5 using NBP2-11982AF647 in the following applications:

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer
Spectra Viewer

Flow Cytometry Panel Builder

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Advanced Features

  • Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
  • Spillover Popups - Visualize the spectra of individual fluorochromes
  • Antigen Density Selector - Match fluorochrome brightness with antigen density
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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: TROP-2

TROP2 encodes a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. [provided by RefSeq]

Long Name

Tumor-associated Calcium Signal Transducer 2

Alternate Names

GA733-1, gp50, T16, TACSTD2, TROP2

Gene Symbol

TACSTD2

Additional TROP-2 Products

Product Documents for TROP-2 Antibody (MM0588-49D6) [Alexa Fluor® 647]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for TROP-2 Antibody (MM0588-49D6) [Alexa Fluor® 647]

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for TROP-2 Antibody (MM0588-49D6) [Alexa Fluor® 647] (1)

5 out of 5
1 Customer Rating
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Customer Images

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  • TROP-2 Antibody (MM0588-49D6) [Alexa Fluor® 647]
    Name: Anonymous
    Application: Flow Cytometry
    Sample Tested: A431 human epithelial carcinoma cell line
    Species: Human
    Verified Customer | Posted 12/10/2023
    Detection of human TROP-2 on A431 epidermoid carcinoma cells. A431 cells were treated with the TROP-2 AF647 antibody (catalog # NBP2-11982AF647) (BLUE) or mouse IgG2 AF647 isotype control antibody (RED)
    A-431 human cancer cell lines were cultured in DMEM + 10% FBS. The cells were detached with accutase and 100,000 cells were stained with TROP-2 AF647-conjugated antibody for 30 minutes. TROP-2 expression was detected in a cytoflex LX.
    TROP-2 Antibody (MM0588-49D6) [Alexa Fluor® 647] NBP2-11982AF647

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