Tropisetron hydrochloride

  ( 4 citations )    
Product Datasheet
Catalog Number:2459
Alternate Names:Novaban, ICS 205930
Chemical Name:(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylic acid ester monohydrochloride
Product Details
Citations (4)
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Biological Activity
Potent, orally active 5-HT3 receptor antagonist. Antiemetic. Also partial agonist of α7 nAChR.
Technical Data
  • M.Wt:
    320.82
  • Formula:
    C17H20N2O2.HCl
  • Solubility:
    Soluble to 100 mM in water and to 50 mM in DMSO
  • Purity:
    >99
  • Storage:
    Desiccate at RT
  • CAS No:
    105826-92-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Tropisetron hydrochloride include:

4 Citations: Showing 1 - 4
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  1. Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms.
    Authors: Otvos Et al.
    Respir Physiol Neurobiol  2015;7:2336
  2. Hypoxia switches episodic breathing to singlet breathing in red-eared slider turtles (Trachemys scripta) via a tropisetron-sensitive mechanism.
    Authors: Johnson Et al.
    Proc Natl Acad Sci U S A  2015;207:48
  3. The multi-functional drug tropisetron binds APP and normalizes cognition in a murine Alzheimer's model.
    Authors: Spilman Et al.
    Brain Res  2014;1551:25
  4. Spatiotemporal pattern of action potential firing in developing inner hair cells of the mouse cochlea.
    Authors: Sendin Et al.
    Mol Cell Biol  2014;111:1999

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