Recombinant Human tropomyosin-3 His Protein

Name: Recombinant Human tropomyosin-3 His Protein
Brand: Novus Biologicals
SKU: NBP1-78867
Price: 349 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-78867

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE

View all tropomyosin-3 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-248 of Human tropomyosin-3

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMAGITT IEAVKRKIQV LQQQADDAEE RAERLQREVE GERRAREQAE AEVASLNRRI QLVEEELDRA QERLATALQK LEEAEKAADE SERGMKVIEN RALKDEEKME LQEIQLKEAK HIAEEADRKY EEVARKLVII EGDLERTEER AELAESRCRE MDEQIRLMDQ NLKCLSAAEE KYSQKEDKYE EEIKILTDKL KEAETRAEFA ERSVAKLEKT IDDLEDKLKC TKEEHLCTQR MLDQTLLDLN EM

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

31.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human tropomyosin-3 His Protein

SDS-PAGE: Recombinant Human tropomyosin-3 His Protein [NBP1-78867]

SDS-Page: Recombinant Human tropomyosin-3 His Protein [NBP1-78867] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation, and Storage

NBP1-78867

Formulation	20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 20% glycerol, 0.1 M NaCl
Preservative	No Preservative
Concentration	0.5 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: tropomyosin-3

Tropomyosin alpha-3 chain, also known as TPM3, is member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Recombinant human TPM3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

cytoskeletal tropomyosin TM30, FLJ41118, gamma-tropomyosin, heat-stable cytoskeletal protein 30 kDa, hscp30, hTM5, MGC14582, MGC3261, MGC72094, NEM1, OK/SW-cl.5, TM3, TM30, TM30nm, TM-5, TPMsk3, TRK, tropomyosin 3, tropomyosin alpha-3 chain, tropomyosin gamma, Tropomyosin-3, Tropomyosin-5

Gene Symbol

TPM3

Additional tropomyosin-3 Products

Product Documents for Recombinant Human tropomyosin-3 His Protein

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Product Specific Notices for Recombinant Human tropomyosin-3 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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