Ubiquitin Native Protein

Novus Biologicals | Catalog # NBP2-62548

Novus Biologicals
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Key Product Details

Source

Bovine erythrocytes

Accession Number

P62990

Applications

ELISA
View all Ubiquitin Proteins and Enzymes »

Product Specifications

Description

Native bovine ubiquitin.

Source: Bovine erythrocytes

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

8.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Native Protein

Formulation, Preparation, and Storage

NBP2-62548
Formulation Prepared from bovine erythrocytes.
Preservative No Preservative
Concentration Lyoph
Reconstitution Reconstitute with 25 ml distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix vial after reconstitution. For long term storage the addition of 0.09% sodium azide is recommende
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C. After reconstitution store at -20C.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Ubiquitin

Ubiquitin is a highly conserved protein of approximately 8.5kDa molecular weight, which has a normal role in the targeting of proteins for proteolytic degradation. To perform this function, the protein to be degraded is first covalently attached to the C-terminus of ubiquitin, and the ubiquitinated complex is then recognized by a complex of degradative enzymes. Interestingly, ubiquitin also becomes covalently bonded to many types of pathological inclusions, which appear to be resistant to normal degradation. Therefore, ubiquitin antibodies are very useful for studies of these inclusions. For example, the neurofibrillary tangles and paired helical filaments diagnostic of Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease are all heavily ubiquitinated and can be readily visualized with ubiquitin antibodies.

Alternate Names

UBB

Gene Symbol

RPS27A

UniProt

P62990 (Bovine)

Additional Ubiquitin Products

Product Documents for Ubiquitin Native Protein

Certificate of Analysis

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Product Specific Notices for Ubiquitin Native Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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