UCM 707

Key Product Details

Product Description

UCM 707 is a potent endocannabinoid transport inhibitor. IC₅₀ values are 0.8 and 30 μM for inhibition of the anandamide transporter and FAAH respectively. K_i values are 4700, 67 and > 5000 nM for CB₁, CB₂ and VR1 receptors respectively. Potentiates hypokinetic and antinociceptive effects of anandamide in vivo.

Product Specifications for UCM 707

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for UCM 707

The following data is based on the product molecular weight 383.57.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.61 mL	13.04 mL	26.07 mL
5 mM	0.52 mL	2.61 mL	5.21 mL
10 mM	0.26 mL	1.30 mL	2.61 mL
50 mM	0.05 mL	0.26 mL	0.52 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Lopez-Rodriguez Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: comparison with effects on fatty acid amidohydrolase. J.Med.Chem. 2003 PMID: 12672252
• Lopez-Rodriguez Design, synthesis and biological evaluation of new endocannabinoid transporter inhibitors. Eur.J.Med.Chem. 2003 PMID: 12750028

Product Documents for UCM 707