Recombinant Mouse UDP glucose dehydrogenase His Protein

Novus Biologicals | Catalog # NBP2-61452

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

Enzyme Activity, SDS-PAGE
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Product Specifications

Description

A recombinant protein with a N-terminalHis-tag and corresponding to the amino acids 1-493 of Mouse UDP glucose dehydrogenase.

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMVEIKKI CCIGAGYVGG PTCSVIAHMC PEIRVTVVDV NEARINAWNS PTLPIYEPGL KEVVESCRGK NLFFSTNIDD AIREADLVFI SVNTPTKTYG MGKGRAADLK YIEACARRIV QNSNGYKIVT EKSTVPVRAA ESIRRIFDAN TKPNLNLQVL SNPEFLAEGT AIKDLKNPDR VLIGGDETPE GQKAVRALCA VYEHWVPKEK ILTTNTWSSE LSKLAANAFL AQRISSINSI SALCEATGAD VEEVATAIGM DQRIGNKFLK ASVGFGGSCF QKDVLNLVYL CEALNLPEVA RYWQQVIDMN DYQRRRFASR IIDSLFNTVT DKKIAILGFA FKKDTGDTRE SSSIYISKYL MDEGAHLHIY DPKVPREQIV VDLSHPGVSA DDQVSRLVTI SKDPYEACDG AHALVICTEW DMFKELDYER IHKKMLKPAF IFDGRRVLDG LHSELQTIGF QIETIGKKVS SKRIPYTPGE IPKFSLQDPP NKKPKV

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

57.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

Specific activity is > 2,500 pmol/min/ug, and is defined as the amount of enzyme that convert 1.0pmole of UDP-glucose to UDP-glucuronate per minute at pH 8.7 at 37C

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Mouse UDP glucose dehydrogenase His Protein

SDS-PAGE: Recombinant Mouse UDP glucose dehydrogenase His Protein [NBP2-61452]

SDS-PAGE: Recombinant Mouse UDP glucose dehydrogenase His Protein [NBP2-61452]

SDS-Page: Recombinant Mouse UDP glucose dehydrogenase Protein [NBP2-61452] - 15% SDS-Page (3ug)

Formulation, Preparation, and Storage

NBP2-61452
Formulation 20 mM MES buffer (pH5.0), 20% glycerol, 150 mM NaCl, 1 mM EDTA
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: UDP glucose dehydrogenase

UDP glucose dehydrogenase is encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. [provided by RefSeq]

Alternate Names

EC 1.1.1.22, GDH, UDPGDHUDP-glucose dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDP-glucose 6-dehydrogenase, UGD, uridine diphospho-glucose dehydrogenase

Gene Symbol

UGDH

Additional UDP glucose dehydrogenase Products

Product Documents for Recombinant Mouse UDP glucose dehydrogenase His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Mouse UDP glucose dehydrogenase His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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