Water-soluble form of UK 14,304
(Cat. No. 0425). Full α2
adrenergic agonist. Centrally active following systemic administration in vivo
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Specific [3H]UK-14,304 binding in human cortex occurs at multiple high affinity states with α2-adrenergic selectivity and different affinities for GTP.
Andorn et al.
Life Sci., 1988;43:1805
UK-14,304, a potent and selective alpha2-gonist for the characterisation of alpha-adrenoceptor subtypes.
Gene targeting - homing in on α2-adrenoceptor-subtype function.
Macdonald et al.
Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway.
Chopin et al.