Potent and selective fatty acid amide hydrolase (FAAH) inhibitor (IC50
values are 3 and 5 nM in human liver and rat brain, respectively). Exhibits no significant inhibitory activity against a variety of receptors, ion channels and enzymes, including human cannabinoid receptors and rat monoacylglycerol lipase. Displays antiallodynic and antihyperalgesic activity in an inflammatory pain model.
Soluble to 50 mM in DMSO
Store at +4°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
An endocannabinoid mechanism for stress-induced analgesia.
Hohmann et al.
Pharmacological profile of the selective FAAH inhibitor KDS-4103 (URB597).
Piomelli et al.
CNS Drug Rev., 2006;12:21
Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models.
Jayamanne et al.
The citations listed below are publications that use Tocris products. Selected citations for URB 597 include:
Showing Results 1 - 4 of 4