Valsartan

Catalog # Availability Size / Price Qty
4216/10
4216/50
Valsartan | CAS No. 137862-53-4 | Angiotensin AT1 Receptor Antagonists
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Description: High affinity, selective AT1 antagonist
Alternative Names: CGP 48933

Chemical Name: (S)-3-methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid

Purity: ≥99%

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Biological Activity

High affinity AT1 receptor antagonist (Ki = 2.38 nM). Displays 30,000-fold selectivity over AT2 receptors. Inhibits angiotensin II-induced release of aldosterone in vitro. Orally active.

Technical Data

M.Wt:
435.52
Formula:
C24H29N5O3
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
137862-53-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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