Venlafaxine hydrochloride

  ( 2 citations )    
Product Datasheet
Catalog Number:2917
Alternate Names:Wy 45030
Chemical Name:1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride
Product Details
Citations (2)
Supplemental Products
Reviews
Biological Activity
Dual serotonin/noradrenalin re-uptake inhibitor that displays ~ 30-fold higher affinity for SERT than NET (Ki values are 82 and 2480 nM respectively). Antidepressant; increases swimming and climbing behavior in the forced-swim test in rats.
Technical Data
  • M.Wt:
    313.86
  • Formula:
    C17H27NO2.HCl
  • Solubility:
    Soluble to 100 mM in water and to 50 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    99300-78-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Venlafaxine hydrochloride include:

2 Citations: Showing 1 - 2
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  1. Distinct Neuropsychological Mechanisms May Explain Delayed- Versus Rapid-Onset Antidepressant Efficacy.
    Authors: Stuart Et al.
    Proc Natl Acad Sci U S A  2015;40:2165
  2. A translational rodent assay of affective biases in depression and antidepressant therapy.
    Authors: Stuart Et al.
    Neuropsychopharmacology  2013;38:1625

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