Vinblastine sulfate

Tocris Bioscience | Catalog # 1256

Disrupts microtubules
Tocris Bioscience

Key Product Details

Description

Disrupts microtubules
View all Microtubule Binding Compounds »

Product Description

Vinblastine sulfate is a anticancer agent; microtubule disrupter. Induces apoptosis in cultured hepatocytes and human lymphoma cells. Shown to inhibit autophagosome maturation.

Product Specifications for Vinblastine sulfate

Molecular Weight

909.06

Formula

C46H58N4O9.H2SO4

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

Vincaleukoblastine

CAS Number

143-67-9

PubChem ID

241902

InChI Key

KDQAABAKXDWYSZ-JKDPCDLQSA-N

SMILES

OS(O)(=O)=O.[H][C@@]23N(C)C1=CC(OC)=[C@]([C@@]7([C@](OC)=O)C[C@H]6C[C@@](O)(CC)CN(CCC8=C7NC9=C8C=CC=C9)C6)C=C1[C@@]52[C@](N(CC5)CC=C4)([H])[C@]4(CC)[C@@H](OC(C)=O)[C@]([C@](OC)=O)3O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 90.91 100
DMSO 90.91 100

Preparing Stock Solutions for Vinblastine sulfate

The following data is based on the product molecular weight 909.06.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.10 mL 5.50 mL 11.00 mL
5 mM 0.22 mL 1.10 mL 2.20 mL
10 mM 0.11 mL 0.55 mL 1.10 mL
50 mM 0.02 mL 0.11 mL 0.22 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.

Product Documents for Vinblastine sulfate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Vinblastine sulfate

For research use only

⚠ WARNING: This product can expose you to chemicals including Vinblastine sulfate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Related Research Areas

Microtubules

Citations for Vinblastine sulfate

Customer Reviews for Vinblastine sulfate (1)

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  • Paclitaxel, docetaxel, vincristine, vinblastine, colchicine, cisplatin, and mitoxantrone screen for Human epidermal carcinoma
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: Human epidermal carcinoma cell line
    Verified Customer | Posted 11/17/2019
    Human epidermal carcinoma cell line was treated with Paclitaxel, docetaxel, vincristine, vinblastine, colchicine, cisplatin, and mitoxantrone which purchased from Tocris Bioscience.
    Vinblastine sulfate 1256

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