Member of the tuberactinomycin family of antibiotics. Inhibits group I intron splicing and prokaryotic protein synthesis. Freezes bacterial ribosomes in either the pre- or post-translational state. Facilitates trans
-cleavage of the Neurospora
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Modulation of RNA function by aminoglycoside antibiotics.
Schroeder et al.
EMBO J., 2000;19:1
The antibiotic viomycin traps the ribosome in an intermediate state of translocation.
Ermolenko et al.
The allosteric three-site model for the ribosomal elongation cycle.
Hausner et al.
The citations listed below are publications that use Tocris products. Selected citations for Viomycin include:
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