VU 0155069

  ( 2 citations )    
Product Datasheet
Catalog Number:3575
Chemical Name:N-[(1S)-2-[4-(5-Chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-1-methylethyl-2-naphthalenecarboxamide
Product Details
Citations (2)
Reviews
Biological Activity
Potent and selective phospholipase D1 (PLD1) inhibitor (IC50 values are 46 and 933 nM for PLD1 and PLD2 respectively). Inhibits migration of human and mouse breast cancer cell lines in transwell assays.
Technical Data
  • M.Wt:
    499.43
  • Formula:
    C26H27ClN4O2.HCl
  • Solubility:
    Soluble to 100 mM in DMSO and to 50 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    1130067-06-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for VU 0155069 include:

2 Citations: Showing 1 - 2
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  1. Elevated phopholipase D isoform 1 in Alzheimer's disease patient' hippocampus. Relevance to synaptic dysfunction and memory deficits.
    Authors: Krishnan Et al.
    Alzheimers Dement (N Y)  2018;4:89
  2. PEA-15 potentiates H-Ras-mediated epithelial cell transformation through phospholipase D.
    Authors: Sulzmaier Et al.
    Oncogene  2012;31:3547

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