Potent and selective phospholipase D1 (PLD1) inhibitor (IC50
values are 46 and 933 nM for PLD1 and PLD2 respectively). Inhibits migration of human and mouse breast cancer cell lines in transwell assays.
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All Tocris products are intended for laboratory research use only.
Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness.
Scott et al.
Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity.
Lewis et al.
The citations listed below are publications that use Tocris products. Selected citations for VU 0155069 include:
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