VU 0364739 hydrochloride

Key Product Details

Product Description

VU 0364739 hydrochloride is a potent and selective phospholipase D2 (PLD2) inhibitor (IC₅₀ = 20 nM); displays 75-fold selectivity against PLD1 (IC₅₀ = 1500 nM).

Product Specifications for VU 0364739 hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for VU 0364739 hydrochloride

The following data is based on the product molecular weight 482.98.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.07 mL	10.35 mL	20.70 mL
5 mM	0.41 mL	2.07 mL	4.14 mL
10 mM	0.21 mL	1.04 mL	2.07 mL
50 mM	0.04 mL	0.21 mL	0.41 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 7 publications citing the usage of this product.

• Lavieri Design, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor. J.Med.Chem.

Product Documents for VU 0364739 hydrochloride