Potent and selective phospholipase D2 (PLD2) inhibitor (IC50
= 20 nM); displays 75-fold selectivity against PLD1 (IC50
= 1500 nM).
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All Tocris products are intended for laboratory research use only.
Design, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor.
Lavieri et al.
The citations listed below are publications that use Tocris products. Selected citations for VU 0364739 hydrochloride include:
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