VUF 10460

   
Product Datasheet
Catalog Number:4769
Chemical Name:4-(4-Methyl-1-piperazinyl)-6-phenyl-2-Pyrimidinamine
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Biological Activity
Selective histamine H4 receptor agonist; displays 50-fold selectivity for the rat H4 receptor over the H3 subtype (pKi values are 5.75 and 7.46 for rat H3 and H4 receptors respectively). Also exhibits affinity for the human H4 receptor (pKi = 8.22).
Technical Data
  • M.Wt:
    269.34
  • Formula:
    C15H19N5
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in 2eq.HCl
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    1028327-66-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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VersaClone cDNA Plasmids
Description Application Cat# Citations Images  

Human Histamine H4 R (NP_067637) VersaClone cDNA

RDC0345
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Mouse Histamine H4 R (NP_694727) VersaClone cDNA

RDC0714
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