VUF 10460

Catalog # Availability Size / Price Qty
4769/10
4769/50
Histamine H4 Receptor Agonists Small Molecule
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Description: Selective H4 agonist

Chemical Name: 4-(4-Methyl-1-piperazinyl)-6-phenyl-2-Pyrimidinamine

Purity: ≥98%

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Biological Activity

Selective histamine H4 receptor agonist; displays 50-fold selectivity for the rat H4 receptor over the H3 subtype (pKi values are 5.75 and 7.46 for rat H3 and H4 receptors respectively). Also exhibits affinity for the human H4 receptor (pKi = 8.22).

Technical Data

M.Wt:
269.34
Formula:
C15H19N5
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in 2eq.HCl
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1028327-66-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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