WAY 181187 oxalate

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5589/10
5589/50
Cat.No. 5589 - WAY 181187 oxalate | C15H13ClN4O2S2.C2H2O4 | CAS No. 1883548-85-3
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Description: High affinity and selective 5-HT6 agonist

Chemical Name: 1-[(6-Chloroimidazo[2,1-b]thiazol-5-yl)sulfonyl]-1H-indole-3-ethanamine oxalate

Purity: ≥98%

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Biological Activity

High affinity and selective 5-HT6 agonist (Ki = 2.2 nM). Displays 60-fold selectivity over other 5-HT and monoamine receptors. Increases firing rate of 5-HT neurons. Modifies sleep and wakefulness profiles following direct injections into the dorsal raphe nucleus, in vivo. Orally bioavailable.

Technical Data

M.Wt:
470.91
Formula:
C15H13ClN4O2S2.C2H2O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
1883548-85-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc

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