Wiskostatin

  ( 1 citations )    
Product Datasheet
Catalog Number:4434
Chemical Name:3,6-Dibromo-α-[(dimethylamino)methyl]-9H-cabazole-9-ethanol
Product Details
Citations (1)
Reviews
Biological Activity
Inhibitor of neural Wiskott-Aldrich syndrome protein (N-WASP) activity. Interacts with the regulatory GTPase-binding domain of N-WASP; inhibits activation of Arp2/3 complex by maintaining N-WASP in an inactive conformation. Also inhibits PIP2-induced actin polymerization (EC50 ~ 4μM).
Technical Data
  • M.Wt:
    426.15
  • Formula:
    C17H18Br2N2O
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    253449-04-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Wiskostatin include:

1 Citations: Showing 1 - 1

  1. Cellular regulation of extension and retraction of pseudopod-like blebs produced by nanosecond pulsed electric field (nsPEF).
    Authors: Rassokhin and Pakhomov
    Cell Biochem Biophys  2014;69:555

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