Wiskostatin

Catalog # Availability Size / Price Qty
4434/10
4434/50
Wiskostatin | CAS No. 253449-04-6 | Actin-related Products
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Description: N-WASP inhibitor; inhibits Arp2/3 activation

Chemical Name: 3,6-Dibromo-α-[(dimethylamino)methyl]-9H-cabazole-9-ethanol

Purity: ≥99%

Product Details
Citations (1)
Reviews

Biological Activity

Inhibitor of neural Wiskott-Aldrich syndrome protein (N-WASP) activity. Interacts with the regulatory GTPase-binding domain of N-WASP; inhibits activation of Arp2/3 complex by maintaining N-WASP in an inactive conformation. Also inhibits PIP2-induced actin polymerization (EC50 ~ 4μM).

Technical Data

M.Wt:
426.15
Formula:
C17H18Br2N2O
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
253449-04-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for Wiskostatin

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