WM 3835

Catalog # Availability Size / Price Qty
7366/50
7366/10

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WM 3835 | CAS No. 2229025-70-9 | Histone Acetyltransferase Inhibitors
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Description: Lysine acetyltransferase HBO1 (KAT7) inhibitor

Chemical Name: N'-(4-Fluoro-5-methyl-[1,1'-biphenyl]-3-carbonyl)-3-hydroxybenzenesulfonohydrazide

Purity: ≥98%

Product Details
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Biological Activity

WM 3835 is a lysine acetyltransferase HBO1 (KAT7) inhibitor. Reduces H3K14ac levels and inhibits growth and viability of acute myeloid leukemia cell lines in vitro. Cell-permeable.

Technical Data

M.Wt:
400.42
Formula:
C20H17FN2O4S
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2229025-70-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. HBO1 is required for the maintenance of leukaemia stem cells.
    MacPherson et al.
    Nature, 2019;577:299

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