Chemical Name: N'-(4-Fluoro-5-methyl-[1,1'-biphenyl]-3-carbonyl)-3-hydroxybenzenesulfonohydrazide
Biological ActivityWM 3835 is a lysine acetyltransferase HBO1 (KAT7) inhibitor. Reduces H3K14ac levels and inhibits growth and viability of acute myeloid leukemia cell lines in vitro. Cell-permeable.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
HBO1 is required for the maintenance of leukaemia stem cells.
MacPherson et al.
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