WM 3835

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WM 3835 | CAS No. 2229025-70-9 | Histone Acetyltransferase Inhibitors
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Description: Lysine acetyltransferase HBO1 (KAT7) inhibitor

Chemical Name: N'-(4-Fluoro-5-methyl-[1,1'-biphenyl]-3-carbonyl)-3-hydroxybenzenesulfonohydrazide

Purity: ≥98%

Product Details

Biological Activity

WM 3835 is a lysine acetyltransferase HBO1 (KAT7) inhibitor. Reduces H3K14ac levels and inhibits growth and viability of acute myeloid leukemia cell lines in vitro. Cell-permeable.

Technical Data

Soluble to 100 mM in DMSO and to 50 mM in ethanol
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. HBO1 is required for the maintenance of leukaemia stem cells.
    MacPherson et al.
    Nature, 2019;577:299

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