WRW4

Catalog # Availability Size / Price Qty
2262/1
WRW4
1 Image
Description: Selective FPR2 antagonist
Alternative Names: WRW4
Product Details
Citations (8)
Supplemental Products
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Biological Activity

Selective antagonist of formyl peptide receptor 2 (FPR2) signaling. Inhibits WKYMVm binding to FPR2 (IC50 = 0.23 μM) and inhibits intracellular calcium release induced by WKYMVm, MMK 1, amyloid β42, and F peptide. Also inhibits FPR2-mediated signaling in human neutrophils; blocks chemotactic migration and superoxide generation by amyloid β42 peptide.

Technical Data

M.Wt:
1104.28
Formula:
C61H65N15O6
Sequence:
WRWWWW

(Modifications: Trp-6 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
878557-55-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for WRW4

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8 Citations: Showing 1 - 8

FAQs

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