Selective antagonist of formyl peptide receptor 2 (FPR2) signaling. Inhibits WKYMVm binding to FPR2 (IC50
= 0.23 μ
M) and inhibits intracellular calcium release induced by WKYMVm, MMK 1, amyloid β
42, and F peptide. Also inhibits FPR2-mediated signaling in human neutrophils; blocks chemotactic migration and superoxide generation by amyloid β
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Identification of peptides that antagonize formyl peptide receptor-like 1-mediating signaling.
Bae et al.
The citations listed below are publications that use Tocris products. Selected citations for WRW4 include:
Showing Results 1 - 5 of 5