Catalog Number: 3040
Chemical Name: (1R*,2S*)-N-(4-Methoxyphenyl)-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide
Biological Activity
Potent TRPM8 agonist that acts as a cooling agent (EC50 = 193 nM).
Technical Data
  • M.Wt:
    289.41
  • Formula:
    C18H27NO2
  • Solubility:
    Soluble to 75 mM in ethanol
  • Purity:
    >99%
  • Storage:
    Store at -20°C
  • CAS No:
    68489-09-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators.
    Beck et al.
    Cell Calcium, 2007;41:285
  2. Characterisation of TRPM8 as a pharmacophore receptor.
    Bodding et al.
    Cell Calcium, 2007;42:618
Citations:

The citations listed below are publications that use Tocris products. Selected citations for WS 12 include:

1 Citations: Showing 1 - 1

  1. Genetic variants affecting human TRPA1 or TRPM8 structure can be classified in vitro as 'well expressed', 'poorly expressed' or 'salvageable'.
    Authors: Morgan Et al.
    Biosci Rep 2015;35

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