Catalog Number: 3252
Chemical Name: N-Methyl-N-[[3-(4-pyridinyl)phenyl]methyl]-4'-(aminocarbonyl)[1,1'-biphenyl]-4-yl carbamic acid ester
Biological Activity
Potent inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50 = 70 nM), an enzyme which catalyzes the hydrolysis of 2-arachidonylglycerol (Cat. No. 1298).
Technical Data
  • M.Wt:
    437.49
  • Formula:
    C27H23N3O3
  • Solubility:
    Soluble to 10 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at +4°C
  • CAS No:
    947669-91-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonylglycerol.
    Blankman et al.
    Chem.Biol., 2007;14:1347
  2. A functional proteomic strategy to discover inhibitors for uncharacterized hydrolases.
    Li et al.
    J.Am.Chem.Soc., 2007;129:9594
Citations:

The citations listed below are publications that use Tocris products. Selected citations for WWL 70 include:

1 Citations: Showing 1 - 1

  1. Selective inhibition of alpha/beta-hydrolase domain 6 attenuates neurodegeneration, alleviates blood brain barrier breakdown, and improves functional recovery in a mouse model of traumatic brain injury.
    Authors: Tchantchou and Zhang
    J Neurotrauma 2013;30:565

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