Xamoterol hemifumarate

Key Product Details

Product Description

Xamoterol hemifumarate is a β₁-adrenoceptor-selective partial agonist (pA₂ values are 7.4 - 7.8 and 5.2 - 6.2 at β₁- and β₂-adrenoceptors respectively).

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Product Specifications for Xamoterol hemifumarate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Xamoterol hemifumarate

The following data is based on the product molecular weight 397.43.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

4 3 2 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.52 mL	12.58 mL	25.16 mL
5 mM	0.50 mL	2.52 mL	5.03 mL
10 mM	0.25 mL	1.26 mL	2.52 mL
50 mM	0.05 mL	0.25 mL	0.50 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 21 publications citing the usage of this product.

• Malta The in vitro pharmacology of xamoterol (ICI 118,587). Br.J.Pharmacol. 1985 PMID: 2862938
• Nuttall and Snow The cardiovascular effects of ICI 118,587: a β₁-adrenoceptor partial agonist. Br.J.Pharmacol. 1982 PMID: 6128041
• Barlow β-Adrenoceptor stimulant properties of aminoalkylamino-substituted 1-aryl-2-ethanols and 1-(aryloxy)-2-propanols. J.Med.Chem. 1981 PMID: 6115058

Product Documents for Xamoterol hemifumarate