Catalog Number: 0950
Alternate Names: ICI 118,587
Chemical Name: 1-(4-Hydroxyphenoxy)-3-[2-(4-morpholinocarboxamido)ethylamino]-2-propanol hemifumarate
Biological Activity
β1-adrenoceptor-selective partial agonist (pA2 values are 7.4 - 7.8 and 5.2 - 6.2 at β1- and β2-adrenoceptors respectively).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in water and to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of AstraZeneca UK Ltd.
Background References
  1. β-Adrenoceptor stimulant properties of aminoalkylamino-substituted 1-aryl-2-ethanols and 1-(aryloxy)-2-propanols.
    Barlow et al.
    J.Med.Chem., 1981;24:315
  2. The in vitro pharmacology of xamoterol (ICI 118,587).
    Malta et al.
    Br.J.Pharmacol., 1985;85:179
  3. The cardiovascular effects of ICI 118,587: a β1-adrenoceptor partial agonist.
    Nuttall and Snow
    Br.J.Pharmacol., 1982;77:381
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