Catalog Number: 4220
Chemical Name: 2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetic acid
Biological Activity
Adenosine receptor antagonist (Ki values are 42, 68 and 1130 nM for A1, A2B and A2A receptors).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Autoradiographic characterization of high-affinity adenosine A2 receptors in the rat brain.
    Jarvis et al.
    Brain Res., 1989;484:111
  2. The inhibitory adenosine receptor at the neuromuscular junction and hippocampus of the rat: antagonism by 1,3,8-substituted xanthines.
    Sebastiao et al.
    Br.J.Pharmacol., 1990;101:453
  3. Adenosine receptor antagonists induce persistent bursting in the rat hippocampal CA3 region via an NMDA receptor-dependent mechanism.
    Thummler and Dunwiddie
    J.Neurophysiol., 2000;83:1787
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