XL 413 hydrochloride

Catalog # Availability Size / Price Qty
5493/10
5493/50
Cat.No. 5493 - XL 413 hydrochloride | C14H12ClN3O2.HCl | CAS No. 1169562-71-3
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Description: Potent and selective Cdc7 inhibitor
Alternative Names: BMS 863233

Chemical Name: 8-Chloro-2-(2S)-2-pyrrolidinylbenzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride

Product Details
Reviews

Biological Activity

Potent and selective Cdc7 inhibitor (IC50 = 3.4 nM). Exhibits >12-fold selectivity for Cdc7 over PIM-1 kinase and >30-fold selectivity over pMCM and CK2. Inhibits proliferation of Colo 205 cells in vitro and attenuates tumor growth of Colo 205 xenografts in mice.

Technical Data

Formula:
C14H12ClN3O2.HCl
Solubility:
Soluble to 20 mM in water
Storage:
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
CAS No:
1169562-71-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Product Datasheets

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