YE 120

Key Product Details

Product Description

YE 120 is a GPR35 agonist (EC₅₀ = 32 nM in DMR assays). Also displays partial agonist activity in a β-arrestin translocation assay (EC₅₀ = 10.2 μM).

Product Specifications for YE 120

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for YE 120

The following data is based on the product molecular weight 330.17.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.03 mL	15.14 mL	30.29 mL
5 mM	0.61 mL	3.03 mL	6.06 mL
10 mM	0.30 mL	1.51 mL	3.03 mL
50 mM	0.06 mL	0.30 mL	0.61 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Deng Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2-carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonists. J.Med.Chem. 2011 PMID: 21950657

Product Documents for YE 120