YH 239-EE

Catalog #: 6719 Datasheet / COA / SDS

Discontinued Product

6719 has been discontinued.
View all Ubiquitin Ligase (E3) Inhibitors products.
YH 239-EE | CAS No. 1364488-67-4 | Ubiquitin Ligase (E3) Inhibitors
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Description: Promotes survival of muscle stem cells (MuSCs); MDM2 inhibitor; activates p53 activity

Chemical Name: Ethyl 3-[2-(tert-butylamino)-1-[N-(4-chlorobenzyl)formamido]-2-oxoethyl]-6-chloro-1H-indole-2-carboxylate

Purity: ≥98%

Product Details

Biological Activity

YH 239-EE is a MDM2 inhibitor. Disrupts MDM2-p53 and activates p53 activity in vitro. Prevents mitotic catastrophe and promotes survival of aged muscle stem cells (muSCs). Also inhibits proliferation of AML cells in vitro.

Technical Data

Soluble to 100 mM in DMSO and to 20 mM in ethanol
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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