20 results for "ACE-2 Proteins and Enzymes" in Products
ACE-2 Proteins and Enzymes
Angiotensin converting enzyme 2 (ACE-2), also known as ACEH (ACE homolog), is an integral membrane protein and a zinc metalloprotease of the ACE family. The predicted human ACE-2 protein sequence consists of 805 amino acids, including a N-terminal signal peptide, a single catalytic domain, a C-terminal membrane anchor, and a short cytoplasmic tail. ACE-2 cleaves angiotensins I and II as a carboxypeptidase.
ACE-2 also serves as the receptor for the SARS-CoV and SARS-CoV-2 viruses. Binding of the S1 domain of the SARS Coronavirus Spike protein to ACE-2 initiates viral entry into the host cell. Recently, this interaction between SARS-CoV-2 and ACE-2 has become an area of intense therapeutic interest to develop treatments against COVID-19.
Analyzed by SEC-MALS
| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | Q9BYF1 |
| Applications: | Bioactivity, Enzyme Activity |
Bioactive, High Spike RBD Binding
| Reactivity: | Human |
| Source: | CHO |
| Accession #: | Q9BYF1.2 |
| Applications: | Bioactivity, Enzyme Activity |
| Reactivity: | Mouse |
| Source: | CHO |
| Accession #: | NP_081562 |
| Applications: | Enzyme Activity |
| Reactivity: | Hamster |
| Source: | HEK293 |
| Accession #: | XP_005074266.1 |
| Applications: | Bioactivity, Enzyme Activity |
| Reactivity: | Cynomolgus Monkey |
| Source: | NS0 |
| Accession #: | XP_005593094.1 |
| Applications: | Bioactivity, Enzyme Activity |
| Reactivity: | Porcine |
| Source: | HEK293 |
| Accession #: | NP_001116542.1 |
| Applications: | Enzyme Activity |
HEK293 Expressed
| Reactivity: | Canine |
| Source: | HEK293 |
| Accession #: | NP_001158732.1 |
| Applications: | Enzyme Activity |
| Reactivity: | Chicken |
| Source: | HEK293 |
| Accession #: | QEQ50331.1 |
| Applications: | Enzyme Activity |
| Reactivity: | Ferret |
| Source: | HEK293 |
| Accession #: | NP_001297119.1 |
| Applications: | Enzyme Activity |
| Reactivity: | Rat |
| Source: | NS0 |
| Accession #: | NP_001012006 |
| Applications: | Enzyme Activity |
| Reactivity: | Human |
| Source: | Synthetic |
| Applications: | AC |
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
| Reactivity: | Human |
| Source: | Synthetic |
| Applications: | AC |
Biotinylated via Amines
| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | Q9BYF1.2 |
| Applications: | Bioactivity, Enzyme Activity |
Biotinylated
| Reactivity: | Human |
| Source: | CHO |
| Accession #: | Q9BYF1.2 |
| Applications: | Bioactivity, Enzyme Activity |
Biotinylated
| Reactivity: | Human |
| Source: | CHO |
| Accession #: | Q9BYF1.2 |
| Applications: | Bioactivity, Enzyme Activity |
| Reactivity: | Human |
| Source: | CHO |
| Applications: | Bioactivity, Enzyme Activity |
| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | Q9BYF1.2 |
| Applications: | Bioactivity |
| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | Q9BYF1.2 |
| Applications: | Bioactivity |
