Adenosine A2a Receptor Agonists

Adenosine A_2A receptors are members of the adenosine receptor group of G-protein-coupled receptors that also includes A₁, A_2B and A₃. A_2A receptors display high expression levels in the spleen, thymus, leukocytes, blood platelets, striatopallidal GABAergic neurons and the olfactory bulb. Lower expression levels are also found in the heart, lungs and blood vessels. A_2A receptors mediate a sustained cardioprotective function during cardiac ischemia, inhibit neutrophil degranulation in ...