Apelin Receptor Antagonists: Products

APJ is a G-protein coupled receptor that is related to the angiotensin receptor. It is primarily expressed in coronary artery endothelium and binds the endogenous ligand, apelin. Apelin signaling through APJ was found to be essential for normal vascular development in frog embryo.

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ML 221 

Apelin antagonist

MM 54 

Potent apelin antagonist
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