Catalog Number: 5992
Biological Activity
Potent apelin receptor antagonist (Ki = 82 nM; IC50 = 93 nM). Antagonizes the inhibitory affect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells.
Technical Data
  • M.Wt:
    1737.15
  • Formula:
    C70H121N29O15S4
  • Sequence:
    CRPRLCKHCRPRLC

    (Modifications: Disulfide bridge: 1-6,9-14)

  • Solubility:
    Soluble to 2 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    1313027-43-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Discovery of a competitive apelin receptor (APJ) antagonist.
    Macaluso et al.
    ChemMedChem, 2011;6:1017
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