MM 54

Tocris Bioscience | Catalog # 5992

Potent apelin antagonist
Tocris Bioscience
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Key Product Details

Description

Potent apelin antagonist
View all Apelin Receptor Antagonists »

Product Description

MM 54 is a potent apelin receptor antagonist (Ki = 82 nM; IC50 = 93 nM). Antagonizes the inhibitory affect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. Recuces tumor expansion and lengthens survival time in a mouse xenograft model of glioblastoma.

Product Specifications for MM 54

Molecular Weight

1737.15

Formula

C70H121N29O15S4

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

1313027-43-8

PubChem ID

122705991

InChI Key

BMJYNYGARUVBJU-CSRTWURCSA-N

SMILES

[H]N[C@H]1CSSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 2mg/ml in water

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

Product Documents for MM 54

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for MM 54

For research use only

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