4 results for "Aryl Hydrocarbon Receptor Agonists" in Products
Aryl Hydrocarbon Receptor Agonists
Aryl hydrocarbon receptors (AHRs) are cytosolic transcription factors that exist bound to co-chaperones in the resting state (Hsp90, prostaglandin E synthase 3 and hepatitis B virus X-associated protein 2). Ligand binding causes the co-chaperones to dissociate, allowing AHR to translocate to the nucleus, dimerize with AHR nuclear translocator (ARNT) and alter transcription of target genes.
AHR is an evolutionary conserved receptor that has roles in cell proliferation and differentiation and induction of xenobiotic-metabolizing enzymes (for example CYP1A1). The human gene encoding the aryl hydrocarbon receptor has been localized to chromosome 7p15.
p53 inhibitor. Also aryl hydrocarbon receptor agonist
| Chemical Name: | 1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide |
Endogenous agonist for the transcription factor aryl hydrocarbon receptor
| Alternate Names: | Aryl hydrocarbon receptor ligand |
| Chemical Name: | 2-(1H-Indol-3-ylcarbonyl)-4-thiazolecarboxylic acid methyl ester |
| Purity: | ≥98% |
High affinity aryl hydrocarbon receptor (AhR) agonist
| Chemical Name: | 5,11-Dihydroindolo[3,2-b]carbazole-6-carboxaldehyde |
| Purity: | ≥95% |
Potent aryl hydrocarbon receptor (AhR) agonist; orally bioavailable
| Chemical Name: | 10-Chloro-7H-benzimidazo[2,1-a]benz[de]isoquinolin-7-one |
| Purity: | ≥97% |
