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1 result for "Aurora Kinase Degraders Small Molecules and Peptides" in Products
Aurora Kinase Degraders Small Molecules and Peptides
Aurora kinases are a family of three highly homologous serine/threonine kinases that play a critical role in regulating many of the processes that are pivotal to mitosis. Each isoform, Aurora A, Aurora B and Aurora C, has a different function in the control of this process.
Aurora A is involved in regulating many of the early mitotic events where its levels peak, particularly during the G2 phase. One target of Aurora A is cdc25b, a direct regulator of the cyclin B1-Cdk1 complex, which provides ...
| Chemical Name: | trans-4-(3-Chloro-2-fluorophenoxy)-N-(2-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)ethoxy)ethoxy)ethyl)-1-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)cyclohexane-1-carboxamide |
| Purity: | ≥98% |
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