3 results for "Casein Kinase 2 alpha Small Molecules and Peptides" in Products
Casein Kinase 2 alpha Small Molecules and Peptides
Casein kinases are a group of ubiquitous Ser/Thr kinases that phosphorylate key regulatory proteins involved in the control of cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways. CK1 family members share a highly conserved kinase domain but differ in their variable N- and C-terminal domains. The C-termini of the CK1 gamma isoforms carry putative palmitoylation sites. CK2 is a tetrameric kinase comprised of two catalytic subunits (CK2 alpha and/or CK2 alpha‘) and two identical regulatory subunits (CK2 beta).
Selective cell-permeable CK2 inhibitor
| Alternate Names: | NSC 231634 |
| Chemical Name: | 4,5,6,7-Tetrabromobenzotriazole |
| Purity: | ≥98% |
Potent CK2A2 and CK2A1 inhibitor; also inhibits DYRK2
| Chemical Name: | N-[5-[[3-Cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methylphenyl]propanamide |
| Purity: | ≥98% |
Potent and selective CK2α and CK2α' inhibitor. Also blocks CK2-dependent HIF-1α transcription, causes cell-cycle arrest, induces apoptosis in cancer cells and induces stem cell reprogramming
| Alternate Names: | Silmitasertib |
| Chemical Name: | Sodium 5-[(3-Chlorophenyl)amino]benzo[c]-2,6-naphthyridine-8-carboxylate |
| Purity: | ≥98% |
