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3 results for "Caspase-4 Small Molecules and Peptides" in Products
Caspase-4 Small Molecules and Peptides
Caspase-11 (also known as as Caspase-4) is a cysteine-aspartic acid protease that functions in apoptosis initiation and the activation of proinflammatory cytokines. Pro-Caspase-11 is expressed as a zymogen which is cleaved into two subunits, p20 and p10. It is activated by an autocatalytic mechanism or by Caspase-8 mediated cleavage in response to ...
| Reactivity: | Multi-Species |
| Applications: |
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High affinity and selective caspase-4 and caspase 1/ICE inhibitor; orally bioavailable
| Alternate Names: | Belnacasan |
| Chemical Name: | N-(4-Amino-3-chlorobenzoyl)-3-methyl-L-valyl-N-[(2R,3S)-2-ethoxytetrahydro-5-oxo-3-furanyl]-L-prolinamide |
| Purity: | ≥98% |
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Potent and selective inhibitor of caspases 1, 5 and 4
| Purity: | ≥95% |
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