Compounds for ESC/iPSC Proliferation and Renewal

Embryonic stem cells (ESCs) are found in the inner cell mass of blastocysts. They are considered immortal as they have an unlimited capacity for self-renewal in an undifferentiated state. ESCs have the ability to differentiate into cells from all three germ layers (endoderm, mesoderm and ectoderm).

Embryonic stem cells (ESCs) are pluripotent cells and differentiation is tightly controlled by growth factor, cytokines and Epigenetic processes such as DNA methylation and chromatin remodeling. ...