Compounds for ESC/iPSC Proliferation and Renewal: Products

Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component

Y-27632 synthesized to cGMP guidelines

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

Selective inhibitor of TGF-βRI, ALK4 and ALK7

PORCN inhibitor; inhibits Wnt processing and secretion

Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogenesis

Prototypical PI 3-kinase inhibitor; also inhibits other kinases

MEK inhibitor

Potent pan-caspase inhibitor

Potent, selective GSK-3 inhibitor

Potent AMPK activator

Potent GSK-3 inhibitor; also inhibits cdks

Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development

Potent and selective Lck and Src inhibitor; also inhibits SIK

Heparin sulfate antagonist

Enhances survival of human ESCs following enzymatic dissociation

E2F transcription factor inhibitor

STAT3 inhibitor; also blocks cancer stem cell self-renewal

Fluorescent probe that selectively identifies undifferentiated iPS/ES cells