4 results for "CTLA-4 Simple Plex" in Products

CTLA-4 Simple Plex

CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.

Simple Plex Human CTLA-4 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Reactivity: Human
Applications: Simple Plex
Ella Automated ELISA Platform and Simple Plex Human CTLA-4 Assay
(3)

Control for use with Human and Non-Human Primate CTLA-4 Simple Plex Cartridge Kit

Reactivity: Human, Non-human Primate
Applications: Ctrl, Simple Plex
Simple Plex Control for Human CTLA-4
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Simple Plex Non-Human Primate CTLA-4 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Reactivity: Non-human Primate
Applications: Simple Plex
(3)
Customize This Cartridge

Simple Plex cartridges are custom built to fit your needs. Choose from over 350 assays spanning human, mouse, rat, and non-human primate. Just select your sample type, cartridge size (16, 32, or 72 samples), and up to 8 analytes per cartridge.

Reactivity: Human, Mouse, Rat, Non-human Primate
Applications: Simple Plex
Custom Simple Plex Assay Panel
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