2 results for "Degrader Building Blocks Small Molecules and Peptides" in Products
Degrader Building Blocks Small Molecules and Peptides
Tocris provides Building Blocks to support Degrader research and development. Degraders (e.g. PROTAC® molecules, SNIPERs etc) are heterobifunctional small molecules that are modular in design, comprising binding moieties for an E3 ubiquitin ligase and a target protein joined by a linker. Our Degrader components have functional handles for easy conjugation to ligands/linkers of interest. The range includes the most effective and commonly used E3 ubiquitin ligase ligands, functionalized at ...
Binds to LRP1 and facilitates receptor-mediated transcytosis of cargo across the BBB
| Purity: | ≥95% |
Biotinylated angiopep-2, induces internalization and degradation of streptavidin in brain cell lines
| Purity: | ≥95% |
