158 results for "Degrader Building Blocks Small Molecules and Peptides" in Products

Degrader Building Blocks Small Molecules and Peptides

Asialoglycoprotein receptor ligand with PEG linker and carboxylic acid group for onward chemistry

Chemical Name: 36-[[2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-21,21-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-19,26,32-trioxo-4,7,10,13,16,23-hexaoxa-20,27,31-triazahexatriacontanoic acid
Purity: ≥90%
Asialoglycoprotein receptor ligand with PEG linker and carboxylic acid group for onward chemistry
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Biotinylated ASGPR ligand for LYTAC research and development

Purity: ≥90%
Biotinylated ASGPR ligand for LYTAC research and development
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Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names: Pomalidomide - linker 4
Chemical Name: 4-[(5-Aminopentyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
Purity: ≥95%
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
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Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Chemical Name: 4-[(8-Aminooctyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
Purity: ≥95%
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
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Cereblon ligand with alkyl linker and terminal azide for onward chemistry

Chemical Name: 4-[(6-Azidohexyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
Purity: ≥95%
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
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Functionalized VHL building block for copper-free click chemistry

Chemical Name: ((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl ((S)-14-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-15,15-dimethyl-12-oxo-3,6,9-trioxa-13-azahexadecyl)carbamate
Purity: ≥90%
Functionalized VHL building block for copper-free click chemistry
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VHL ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names: (S,R,S)-AHPC-C2-NH2
Chemical Name: (2S,4R)-1-((S)-2-(3-Aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
Purity: ≥95%
VHL ligand with alkyl linker and terminal amine for onward chemistry
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Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Chemical Name: 4-[(6-Aminohexyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
Purity: ≥95%
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
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VHL ligand with PEG linker and terminal acid for onward chemistry

Alternate Names: (S,R,S)-AHPC-PEG4-COOH
Chemical Name: (S)-18-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-19,19-dimethyl-16-oxo-4,7,10,13-tetraoxa-17-azaicosanoic acid
Purity: ≥95%
VHL ligand with PEG linker and terminal acid for onward chemistry
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Functionalized BET bromodomain ligand; precursor for Tag Degraders

Chemical Name: (R)-2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)butanoic acid
Purity: ≥98%
Functionalized BET bromodomain ligand; precursor for Tag Degraders
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VHL ligand with PEG linker and terminal amine for onward chemistry

Alternate Names: (S,R,S)-AHPC-PEG2-NH2
Chemical Name: (2S,4R)-1-((S)-2-(2-(2-(2-Aminoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥95%
VHL ligand with PEG linker and terminal amine for onward chemistry
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Cereblon ligand with alkyl linker and terminal acid for onward chemistry

Chemical Name: 4-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]butanoic acid
Purity: ≥95%
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
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VHL ligand with alkyl linker and terminal acid for onward chemistry

Alternate Names: (S,R,S)-AHPC-C2-COOH
Chemical Name: 4-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-4-oxobutanoic acid
Purity: ≥95%
VHL ligand with alkyl linker and terminal acid for onward chemistry
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Cereblon ligand with PEG linker and terminal acid for onward chemistry

Chemical Name: 3-[2-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]propanoic acid
Purity: ≥95%
Cereblon ligand with PEG linker and terminal acid for onward chemistry
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VHL ligand with alkyl linker and terminal amine for onward chemistry

Chemical Name: (2S,4R)-N-(2-(4-Aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride
Purity: ≥95%
VHL ligand with alkyl linker and terminal amine for onward chemistry
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VHL ligand with alkyl linker and terminal amine for onward chemistry

Chemical Name: (2S,4R)-N-(2-((6-Aminohexyl)oxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride
Purity: ≥95%
VHL ligand with alkyl linker and terminal amine for onward chemistry
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Cereblon ligand with alkyl linker and terminal azide for onward chemistry

Chemical Name: 4-[(2-Azidoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
Purity: ≥95%
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
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Cereblon ligand with terminal piperidine for onward chemistry

Chemical Name: 3-[1,3-Dihydro-1-oxo-5-[4-(4-piperidinylmethyl)-1-piperazinyl]-2H-isoindol-2-yl]-2,6-piperidinedione dihydrochloride
Purity: ≥94%
Cereblon ligand with terminal piperidine for onward chemistry
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Functionalized IAP ligand for PROTACs

Chemical Name: tert-Butyl [(S)-1-[[(S)-2-[(2S,4S)-4-amino-2-[[(R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]amino]-1-oxopropan-2-yl](methyl)carbamate hydrochloride
Purity: ≥98%
Functionalized IAP ligand for PROTACs
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IAP ligand with PEG linker and terminal amine for onward chemistry

Chemical Name: tert-Butyl [(S)-1-[[(S)-2-[(2S,4S)-4-[2-[2-2-[(2-aminoethoxy)ethoxy]ethoxy]acetamido]-2-[[(R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]amino]-1-oxopropan-2-yl](methyl)carbamate
Purity: ≥95%
IAP ligand with PEG linker and terminal amine for onward chemistry
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IAP ligand with PEG linker and terminal amine for onward chemistry

Chemical Name: tert-Butyl [(S)-1-[[(S)-2-[(2S,4S)-4-[2-[2-(2-aminoethoxy)ethoxy]acetamido]-2-[[(R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]amino]-1-oxopropan-2-yl](methyl)carbamate
Purity: ≥95%
IAP ligand with PEG linker and terminal amine for onward chemistry
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IAP ligand with alkyl linker and terminal amine for onward chemistry

Chemical Name: tert-Butyl [(S)-1-[[(S)-2-[(2S,4S)-4-(5-Aminopentanamido)-2-[[(R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]amino]-1-oxopropan-2-yl](methyl)carbamate
Purity: ≥95%
IAP ligand with alkyl linker and terminal amine for onward chemistry
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Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Chemical Name: N-(8-Aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-acetamide hydrochloride
Purity: ≥95%
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
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Cereblon ligand with PEG linker and terminal amine for onward chemistry

Alternate Names: Thalidomide - linker 13
Chemical Name: N-[2-(2-Aminoethoxy)ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide
Purity: ≥95%
Cereblon ligand with PEG linker and terminal amine for onward chemistry
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VHL ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names: (S,R,S)-AHPC-C3-NH2
Chemical Name: (2S,4R)-1-((S)-2-(4-Aminobutanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
Purity: ≥95%
VHL ligand with alkyl linker and terminal amine for onward chemistry
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